Contact Info

alice.shanfelter@uga.edu
Office:
C214 Davison Life Sciences

Broadly, I am interested in the regulation and evolution of recombination between individuals and populations. My current work focuses on sex-specific recombination patterns as little is known about how these patterns form or why they persist over time. My data suggests that changes in chromatin structure during meiosis may lead to these sex-specific patterns and I am working to understand what drives these changes.

Education:

B.S. (2015) Biology, Virginia Commonwealth University

B.S. (2015) Chemistry, Virigina Commonwealth University

Research Areas:
Research Interests:

I am interested in the evolution of recombination rates across genomes. Most recombination occurs in small 1-2kb regions known as hotspots. How hotspots are targeted is variable across species. However, it is important to understand how hotspots are targeted as recombination plays an important role in genome evolution. We use threespine stickleback fish as model system to examine how recombination rates and hotspots change across a short evolutionary time scale between stickleback populations (~ 10,000 years).

Labs (please indicate whose lab you are a member of):
Of note:

Publications:

  • Alice F. Shanfelter, Sophie Archambeault, and Michael A. White. Fine-scale recombination landscapes between a freshwater and marine population of threespine stickleback fish. In Revision. BioRxiv: https://doi.org/10.1101/430249

Positions held/ Professional Affiliations:

  • Graduate Student Representative for UGA Genetics Department Faculty Hire (Nov 2017-Jan 2018)
  • Genetics Graduate Student Evolution Co-Representative (2017-2018)
  • Developmental Biology Graduate Student Association Secretary (2016-2017)
  • Member of Society for Study of Evolution

Presentations:

  • Evolution of Sex-Specific Recombination Rates through Changes in Chromatin Structure, Poster presentation, SEPEEG 2018, Mountain Lake Biological Station, VA
  • Association between Sex-Specific Recombination Rates and Chromatin Structure, Oral presentation, Genetics Fall Retreat 2018, UGA
  • Divergent Fine-Scale Recombination Landscapes Between Populations of Threespine Stickleback Fish, Oral presentation, Stickleback 2018, Kyoto, Japan
  • Hotspots Young and Old: The Effect of Recombination on Genome Evolution, Oral presentation, SEPEEG 2017, Laurel Hill, NC
  • Rapidly Evolving Recombination Hotspots in Threespine Stickleback, Oral presentation, Evolution 2017, Portland, OR
  • Recombination Hotspots in Threespine Stickleback, Oral presentation, EDGE 2017, UGA
  • The Evolution of Fine-Scale Recombination Rates Across the Young Threespine Stickleback Sex Chromosomes, Oral presentation, Evolutionary Genomics of Sex 2016, Tempe, AZ
  • The Evolution of Fine-Scale Recombination Rates in Threespine Stickleback, Oral presentation, SEPEEG 2016, Madison, FL
  • The Evolution of Fine-Scale Recombination Rates in Threespine Stickleback, poster, Evolution 2016, Austin, TX

Awards:

  • Jan and Kirby Alton Fellowship through Department of Genetics,UGA,  2018-present
  • Robin Hightower Award through Department of Genetics, UGA, 2018
  • Genetics Graduate Student Association Travel Award through GGSA, UGA, 2018
  • Student Travel Award through Stickleback 2018, Kyoto, Japan
  • Best Graduate Student Talk, SEPEEG 2017, Laurel Hill, NC
  • T32 NIH Training Grant through Department of Genetics, UGA, 2017-2018
  • Rosemary Grant Award from the Society for the Study of Evolution, 2017
  • Travel Award, Evolutionary Genomics of Sex 2016, Tempe, AZ
  • Best Graduate Student Talk, SEPEEG 2016, Madison, FL