Skip to main content
Skip to main menu Skip to spotlight region Skip to secondary region Skip to UGA region Skip to Tertiary region Skip to Quaternary region Skip to unit footer

Slideshow

Menke Lab ‘Game-changing’ gene edit advances squamate genomics

Image:
Anolis gene edit mutation

CRISPR-Cas9 Gene Editing in Lizards Through Microinjection of Unfertilized Oocytes

CRISPR-Cas9 mediated gene editing has enabled the direct manipulation of gene function in many species. However, the reproductive biology of reptiles presents unique barriers for the use of this technology, and there are currently no reptiles with effective methods for targeted mutagenesis. Here we present a new approach that enables the efficient production of CRISPR-Cas9 induced mutations in Anolis lizards, an important model for studies of reptile evolution and development.

Personnel

Professor, Director, Developmental Biology Alliance, Ph.D. (2002) Massachusetts Institute of Technology

Support Genetics at UGA

Thank you for your support to the Genetics Department and the University of Georgia. Contributions from alumni and friends are critical to maintaining our core missions of teaching and research. Gifts are tax deductible.

Click here to learn more

Every dollar contributed to the department has a direct impact on our students and faculty.