Molecular Genetics

We are interested in the molecular control of myogenesis. Skeletal muscle is the largest tissue in human body. Its formation requires the activation and expansion of muscle stem cells, and subsequent differentiation, fusion and maturation of their progenies. Understanding the mechanisms that drive these cellular events is not only essential to…

Mammalian developmental genetics: mechanisms that control tissue patterns during mammalian embryonic development; signaling pathways that function in cell fate specification; identification of novel regulators of Hedgehog signaling pathways in central nervous system

Systems biology of host-pathogen interactions, Nuclear and organellar genome evolution in eukaryotic parasites, Databases, Ontologies, Data mining and Data integration of 'omics (genome, transcriptome, proteome, metabolome, lipidome), clinical, immunological, epidemiological and experimental metadata.  

I have very broad biology research interests, having worked on organisms from all four eukaryotic kingdoms and eubacteria and archaea. I have employed diverse scientific methods to study biological problems and I have published in the fields of biochemistry, enzymology, protein chemistry, immunology, cell biology, microbiology, genetics,…

Pseudomonas aeruginosa is one of the leading causes of chronic infections due to its ability to form robust, antibiotic tolerant biofilms. It is therefore imperative to better understand bacterial physiology in order to discover new ways to dismantle biofilms and clear infections. Some questions we seek to answer include: 1. What is the…

My research interest lies in Nutritional Genomics, a new interdisciplinary field bridging Nutritional Sciences and Human Genomics. I am interested in identifying genetic variants that historically helped human populations adapt to local diets and currently underlie individual differences in nutrient metabolism and metabolic disease risks. In…