IT Professional Specialist (Retired) EDUCATION Virginia Polytechnic Institute and State University, Blacksburg, VA. Microbiology, 1975-1978, Marine Biological Laboratory, Woods Hole, MA. Microbial Ecology Training Program, Summer 1975, University of West Florida, Pensacola, FL. Estuarine Ecology 1972-1975, University of Michigan, College of Natural Resources. Ann Arbor, MI. Fisheries Biology/Biological Oceanography 1968-1972 EXPERIENCE IT PROFESSIONAL SPECIALIST - Department of Genetics, University of Georgia, Athens, GA 1997-PRESENT LABORATORY COORDINATOR - Department of Genetics, University of Georgia, Athens, GA 1991-1997 MOLECULAR BIOLOGIST. Corporate Molecular Biology, Abbott Laboratories, Abbott Park, IL., 1983 -1991 LABORATORY SPECIALIST - Department of Anaerobic Microbiology, Virginia Polytechnic Institute and State University, Blacksburg, VA, 1979-1983 FIELD TEAM LEADER - U.S. Antarctic Research Program, 1976 & 1977 Austral Summers Selected Publications Selected Publications: Ravagnani, A., K. C. B. Jennert, E. Steiner, R. Grünberg, J. R. Jefferies, S. R. Wilkinson, D. I. Young, E. C. Tidswell, D. P. Brown and P. Youngman (2000). "Spo0A directly controls the switch from acid to solvent production in solvent‐forming clostridia." Molecular microbiology 37(5): 1172-1185. Muchova, K., R. J. Lewis, J. A. Brannigan, W. A. Offen, D. P. Brown, I. Barak, P. Youngman and A. J. Wilkinson (1999). "Crystallization of the regulatory and effector domains of the key sporulation response regulator Spo0A." Acta Crystallographica Section D: Biological Crystallography 55(3): 671-676. Milenbachs, A. A., D. P. Brown, M. Moors and P. Youngman (1997). "Carbon‐source regulation of virulence gene expression in Listeria monocytogenes." Molecular microbiology 23(5): 1075-1085. Barak, I., J. Behari, G. Olmedo, P. Guzman, D. P. Brown, E. Castro and D. Walker (1996.). "Structure and function of the Bacillus SpoIIE 181 protein and its localization to sites of sporulation septum assembly." Molecular microbiology 182(19): 1047-1060. Barák, I., J. Behari, G. Olmedo, P. Guzmán, D. P. Brown, E. Castro, D. Walker, J. Westpheling and P. Youngman (1996). "Structure and function of the Bacillus SpoIIE protein and its localization to sites of sporulation septum assembly." Molecular microbiology 19(5): 1047-1060. Gutierrez, J. A., P. J. Crowley, D. P. Brown, J. D. Hillman, P. Youngman and A. S. Bleiweis (1996). "Insertional mutagenesis and recovery of interrupted genes of Streptococcus mutans by using transposon Tn917: Preliminary characterization of mutants displaying acid sensitivity and nutritional requirements." Journal of bacteriology 178(14): 4166-4175. Brown, D. P., L. Ganova‐Raeva, B. D. Green, S. R. Wilkinson, M. Young and P. Youngman (1994). "Characterization of spo0A homologues in diverse Bacillus and Clostridium species identifies a probable DNA‐binding domain." Molecular microbiology 14(3): 411-426. Brown, D. P., K. B. Idler, D. M. Backer, S. Donadio and L. Katz (1994). "Characterization of the genes and attachment sites for site-specific integration of plasmid pSE101 in Saccharopolyspora erythraea and S i." Molecular and General Genetics MGG 242(2): 185-193. Metzger, R., D. P. Brown, P. Grealish, M. J. Staver, J. Versalovic, J. R. Lupski and L. Katz (1994). "Characterization of the macromolecular synthesis (MMS) operon from Listeria monocytogenes." Gene 151(1): 161-166. Taylor, A., D. P. Brown, S. Kadam, M. Maus, W. E. Kohlbrenner, D. Weigl, M. C. Turon and L. Katz (1992). "High-level expression and purification of mature HIV-1 protease in Escherichia coli under control of the araBAD promoter." Applied microbiology and biotechnology 37(2): 205-210. Katz, L., D. P. Brown and S. Donadio (1991). "Site-specific recombination in Escherichia coli between the att sites of plasmid pSE211 from Saccharopolyspora erythraea " Molecular and General Genetics MGG 227(1): 155-159. Brown, D. P., K. B. Idler and L. Katz (1990). "Characterization of the genetic elements required for site-specific integration of plasmid pSE211 in Saccharopolyspora erythraea." Journal of bacteriology 172(4): 1877-1888. Brown, D. P., S. J. Chiang, J. S. Tuan and L. Katz (1988). "Site-specific integration in Saccharopolyspora erythraea and multisite integration in Streptomyces lividans of actinomycete plasmid pSE101." Journal of bacteriology 170(5): 2287-2295. Brown, D. P., J. S. Tuan, K. A. Boris, K. B. Idler, J. P. Dewitt, S. J. D. Chaing and L. Katz (1988). "Plasmid− chromosome interactions in Saccharopolyspora erythraea and Streptomyces lividans." Developments in industrial microbiology 29: 97-105. Baron, S. F., D. P. Brown and J. G. Ferry (1987). "Locations of the hydrogenases of Methanobacterium formicicum after subcellular fractionation of cell extract." Journal of bacteriology 169(8): 3823-3825. Katz, L., D. P. Brown, K. A. Boris and J. S. Tuan (1987). "Expression of the MLS resistance methylase gene ermE from Streptomyces erythreus in Escherichia coliresults in N6,N6-dimethylation of ribosomal RNA." Gene 55: 319-325. McAlpine, J. B., J. S. Tuan, D. P. Brown, K. D. Grebner, D. N. Whittern, A. Buko and L. Katz (1987). "New antibiotics from genetically engineered actinomycetes. I. 2-Norerythromycins, isolation and structural determinations." The Journal of antibiotics 40(8): 1115-1122. Nelson, M. J. K., D. P. Brown and J. G. Ferry (1984). "FAD requirement for the reduction of coenzyme F 420 by hydrogenase from Methanobacterium formicicum." Biochemical and biophysical research communications 120(3): 775-781. Schauer, N. L., D. P. Brown and J. G. Ferry (1982). "Kinetics of formate metabolism in Methanobacterium formicicum and Methanospirillum hungatei." Applied and environmental microbiology 44(3): 549-554. Simmons, G., B. C. Parker, T. A. Allnutt, D. P. Brown and K. G. Seaburg (1979). "Ecological comparisons of oasis lakes and soils." Antarctic Journal U.S. XIV: 181-183. Moshiri, G. A., D. P. Brown and W. G. Crumpton (1977). "An inexpensive and easily fabricated sampler for collecting sediment cores to measure Eh potentials." Florida Scientist 40(2): 203-205. Moshiri, G. A., W. G. Crumpton, D. P. Brown, P. R. Barrington and N. Aumen (1976). "Interrelationships tetween certain microorganisms and some aspects of sediment-water nutrient exchange in two bayou estuaries." Fla. Water Resources Research Center publ. no 37 Moshiri, G. A., D. P. Brown, P. Conklin, D. Gilbert, M. Hughes, M. Moore, D. Ray and L. Robinson (1974). "Nitrogen-Phosphorus budget for Bayou Texar, Pensacola, Florida." Fla. Water Resources Research Center publ.no. 29. Moshiri, G. A., D. P. Brown, R. S. Engert and P. H. Crittenden (1973). "Certain nutrient-primary productivity relations in a bayou Estuary." Quart. J. Fla. Acad. Sci 36(suppl no. 1).
